Oral presentations
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5th World Congress on Alternatives and Animal Use in the Life Sciences, 21-25/08/2005, Berlin-Germany: the effects of Trichostatin A on gap junctional intercellular communication in primary cultures of adult rat hepatocytes.
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Journée Exceptionnelle Connexins, 25/05/2007, Paris-France: the effects of Trichostatin A on gap junctional intercellular communication in primary cultures of adult rat hepatocytes.
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1st annual carcinoGENOMICS consortium meeting, 06-08/11/2007, Valencia-Spain: Trichostatin A enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes.
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Journal Club, 07/07/2009, Ghent-Belgium: connexin32 hemichannels facilitate the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death.
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International Gap Junction Conference, 25-30/07/2009, Sedona-USA: connexin32 hemichannels facilitate the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death.
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CarcinoGENOMICS workpackage 2 meeting, 17-18/08/2008, Gothenburg-Sweden: Trichostatin A-stabilized primary rat hepatocyte cultures: a concise overview.
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7th World Congress on Alternatives and Animal Use in the Life Sciences, 30/08-03/09/2009, Rome-Italy: restoration and maintenance of the in vivo-like hepatocellular homeostatic balance: key for the establishment of long-term liver-based in vitro models.
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ESNATS summer school, 22-27/09/2009, Zermatt-Switzerland: restoration and maintenance of the in vivo-like hepatocellular homeostatic balance: key for the establishment of long-term liver-based in vitro models.
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Research seminars: master of biomedical sciences in cell and gene therapy, 02/04/2010, Brussels-Belgium: connexin-related signaling in cell death.
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ADMET: Translating Research into Clinical Outcome, 06-07/07/2011, London-United Kingdom: state-of-the-art overview of strategies for the establishment of liver-based in vitro systems for long-term pharmaco-toxicological testing.
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8th World Congress on Alternatives and Animal Use in the Life Sciences, 21-25/08/2011, Montréal-Canada: an introduction to epigenetics.
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8th World Congress on Alternatives and Animal Use in the Life Sciences, 21-25/08/2011, Montréal-Canada: the European Society of Toxicology In Vitro: a concise introduction.
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Summer School of the Safety Evaluation Ultimately Replacing Animal Testing project cluster, 04-08/06/2012, Lisbon-Portugal: drug-induced liver injury: mechanisms, types and biomarkers.
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Postgraduate course on gap junctions, connexins and their physiological and pathological roles, 24-28/09/2012, São Paulo-Brazil: study of connexins and the Department of Toxicology of the Vrije Universiteit Brussel (Free University Brussels)-Belgium.
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4th Journey of the Latin American Society of Toxicologic Pathology, 25/09/2012, São Paulo-Brazil: connexin and pannexin signalling in cell death and cell growth: relevance for liver physiology and liver pathology.
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State-of-the-art lectures in Biomedicine, 03/10/2012, Antwerp-Belgium: connexin and pannexin signalling in cell death and cell growth: relevance for liver physiology and liver pathology.
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17th Conference of the European Society for Toxicology In Vitro, 16-19/10/2012, Lisbon-Portugal: the effect of epigenetic modification on drug transporters in primary hepatocyte cultures.
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Winterschool of the HeMiBio project, 16/01/2013, Barcelona-Spain: drug-induced liver injury: mechanisms, types and biomarkers.
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Human Toxicology Project Consortium meeting, 23-25/01/2013, Baltimore-USA: drug-induced liver injury: mechanisms and types.
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ReLiver workshop, 20-22/02/2013, Heidelberg-Germany: drug-induced liver injury: mechanisms and types.
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Summerschool of the DETECTIVE project, 10-14/06/2013, Slano-Croatia: introduction to drug-induced liver injury and adverse outcome pathways.
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49th Conference of the European Societies of Toxicology, 01-04/09/2013, Interlaken-Switzerland: the role of connexins and their channels in toxicity.
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SEURAT-1 Stakeholders event, 05/09/2013, Brussels-Belgium: HeMiBio: engineering tissue.
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XVIII Brazilian Congress of Toxicology, 07-10/10/2013, Porto Alegre-Brazil: in vitro models for the evaluation of hepatotoxicity.
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Specialisation course in the generation and maintenance of laboratory animals, 19/10/2013, Sao Pãulo-Brazil: alternatives to animal testing in toxicology.
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XXII Scientific week Benjamin Eurico Malucelli, 21/10/2013, São Paulo-Brazil, oral presentation: alternatives to animal testing in toxicology.
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State-of-the-art lectures in Biomedicine, 18/12/2013, Antwerp-Belgium: in vitro models for the evaluation of hepatotoxicity.
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Dutch Society of Toxicology meeting, 12/02/2014, Leiden-The Netherlands: the adverse outcome pathway concept: a novel and pragmatic tool in toxicology and risk assessment.
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Research seminars: master of biomedical sciences in cell and gene therapy, 21/02/2014, Brussels-Belgium: the CONNECT project: connexins and pannexins as drug targets and biomarkers in acute and chronic liver disease.
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Human Toxicology Project Consortium meeting, 25/03/2014, Phoenix-USA: development and use of hepatic AOPs in the SEURAT project cluster.
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Connexins-Pannexins: WOG FWO meeting, 22-23/05/2014, Ghent-Belgium: protective effects of connexin43 signaling in experimentally induced acute liver failure in mouse.
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5th symposium of the Latin American Society of Toxicologic Pathology, 11-14/04/2014, São Paulo-Brazil: in vitro models for the evaluation of hepatotoxicity.
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5th symposium of the Latin American Society of Toxicologic Pathology, 11-14/04/2014, São Paulo-Brazil: hepatic adverse outcome pathway constructs: novel and pragmatic tools in toxicology and risk assessment.
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NOTOX satellite meeting, 10/06/2014, Egmond aan zee-The Netherlands: development and use of hepatic AOPs in the SEURAT project cluster.
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OECD meeting of the extended advisory group on molecular screening and toxicogenomics, 12-13/06/2014, Paris-France: development and application of a new AOP from BSEP inhibition to cholestasis.
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9th World Congress on Alternatives and Animal Use in the Life Sciences, 24-28/08/2014, Prague-Czech Republic: development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.
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NIH workshop, 03-05/09/2014, Bethesda-USA: testing of the predictive power and robustness of an AOP construct for bile salt export pump inhibition to cholestatic injury.
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Research seminar Department of Clinical Analysis and Toxicology, University of São Paulo, 30/09/2014, São Paulo-Brazil: liver-based in vitro models: conventional and novel strategies.
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Research seminar Masaryk University, 04/11/2014, Brno-Czech Republic: drug-induced liver injury: mechanisms, types and biomarkers.
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Research seminar Masaryk University, 04/11/2014, Brno-Czech Republic: liver-based in vitro models: conventional and novel strategies.
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Research seminar Masaryk University, 05/11/2014, Brno-Czech Republic: connexins and pannexins: targets and biomarkers of liver disease.
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State-of-the-art lectures in Biomedicine, 05/11/2014, Antwerp-Belgium: in vitro models for the evaluation of hepatotoxicity.
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Seminar at the University of Kansas Medical Center, 12/11/2014, Kansas City-USA: connexins and pannexins: targets and biomarkers of liver disease.
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IVTIP meeting, 18/11/2014, Monte Carlo-Monaco: adverse outcome pathways: development and applications.
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Research seminar Federal University of Minas Gerais, 10/12/2014, Belo Horizonte-Brazil: connexins and pannexins: targets and biomarkers of liver disease.
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Applied in vitro toxicology course, 25-29/01/2015, Lisbon-Portugal: general in vitro cytotoxicity and cell death assays.
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Applied in vitro toxicology course, 25-29/01/2015, Lisbon-Portugal: liver-based models for in vitro toxicology purposes.
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Applied in vitro toxicology course, 25-29/01/2015, Lisbon-Portugal: emerging topics in in vitro toxicology: adverse outcome pathways.
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Research seminar University of Western Ontario, 06/03/2015, London-Canada: connexins and pannexins: targets and biomarkers of liver disease.
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Research seminar Université de Poitiers, 17/03/2015, Poitiers-France: connexins and pannexins: targets and biomarkers of liver disease.
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Society of Toxicology meeting, 22-26/03/2015, San Diego-USA: connexin signaling in liver toxicity and disease.
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Society of Toxicology meeting, 22-26/03/2015, San Diego-USA: predictive power and robustness of an AOP construct for bile salt export pump inhibition to cholestatic injury.
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Research seminar University of São Paulo, 16/04/2015, São Paulo-Brazil: connexins and pannexins: targets and biomarkers of liver disease.
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25th conference of the Society of Environmental Toxicology and Chemistry, 03-07/05/2015, Barcelona-Spain: development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.
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In Vitro Testing Industrial Platform Spring Meeting, 28-29/05/2015, Copenhagen-Denmark: mechanistic understanding of toxicity: an introduction to AOPs and their potential for in vitro testing application.
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Long Range Science Strategy workshop Cosmetics Europe, 02-03/06/2015, Brussels-Belgium: validation and optimization of adverse outcome pathways: the new challenge.
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Network Verification Challenge Jamboree, 15-18/06/2015, Barcelona-Spain: adverse outcome pathways as tools to assess drug-induced toxicity.
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Second World Conference on Targeting Liver Disease, 25-26/06/2015, St-Julian’s-Malta: inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity in mouse.
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Gap Junction Conference: Therapeutic Applications, 24/09/2015, La Coruna-Spain: role of connexin and pannexin signaling in liver disease.
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State-of-the-art lectures in Biomedicine, 14/10/2015, Antwerp-Belgium: in vitro models for the evaluation of hepatotoxicity.
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HeMiBio International Symposium Biology meets technology for liver toxicity testing, 02-03/12/2015, Leuven-Belgium: adverse outcome pathways as tools to assess drug-induced toxicity.
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Seminar SRM University, 27/01/2016, Chennai-India: liver-based in vitro models for toxicity testing.
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Seminar SRM University, 27/01/2016, Chennai-India: adverse outcome pathways as tools to assess chemical toxicity.
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University of Auckland, 08/03/2016, Auckland-New Zealand: role of connexins, pannexins and their channels in liver disease.
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2nd International Conference on Hepatology, 09-11/05/2016, Chicago-USA: connexins and pannexins as novel drug targets in the treatment of acute and chronic liver disease.
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Applied in vitro toxicology course, 20-24/06/2016, Brasilia-Brazil: general in vitro cytotoxicity and cell death assays.
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Applied in vitro toxicology course, 20-24/06/2016, Brasilia-Brazil: liver-based models for in vitro toxicology purposes.
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Alternative Approaches for Acute Inhalation Toxicity to Address Global Regulatory and Non-regulatory Data Requirements Webinar Series, 12/07/2016, Brussels-Belgium: adverse outcome pathways as tools to assess chemical-induced toxicity.
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52th Conference of the European Societies of Toxicology, 04-07/09/2016, Seville-Spain: the adverse outcome pathway for cholestatic liver injury: from mechanisms to predictive human toxicology.
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27th Ion Channel Meeting, 11-14/09/2016, Sète-France: connexin and pannexin (hemi)channels as novel drug targets in liver disease.
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Science Xpression Workshop, 26-28/09/2016, La Coruna-Spain: preparing and giving a scientific presentation: tips and tricks.
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Science Xpression Workshop, 26-28/09/2016, La Coruna-Spain: writing a scientific abstract: tips and tricks.
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Gap Junction Conference: Therapeutic Applications, 29/09/2016, La Coruna-Spain: connexins and pannexins as novel drug targets in the treatment of acute and chronic liver disease.
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Research seminar Department of Clinical Analysis and Toxicology, University of São Paulo, 25/10/2016, São Paulo-Brazil: liver-based in vitro models: conventional and novel strategies.
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Research seminar Department of Clinical Analysis and Toxicology, University of São Paulo, 31/10/2016, São Paulo-Brazil: liver metabolism: phase 0-III biotransformation.
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Research seminar Department of Clinical Analysis and Toxicology, University of São Paulo, 31/10/2016, São Paulo-Brazil: liver toxicity: types and mechanisms.
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State-of-the-art lectures in Biomedicine, 07/12/2016, Antwerp-Belgium: liver-based models for in vitro toxicology purposes.
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Applied in vitro toxicology course, 08-13/01/2017, Belvaux-Luxembourg: general in vitro cytotoxicity and cell death assays.
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Applied in vitro toxicology course, 08-13/01/2017, Belvaux-Luxembourg: liver-based models for in vitro toxicology purposes.
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Applied in vitro toxicology course, 08-13/01/2017, Belvaux-Luxembourg: emerging topics in in vitro toxicology: adverse outcome pathways.
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Adverse outcome pathways: emerging regulatory requirements and new in vitro models webinar series, 06/02/2017, Brussels-Belgium: adverse outcome pathways as tools to address chemically-induced liver toxicity.
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Postgraduate Education in Toxicology: Toxicogenomics, 23/02/2017, Maastricht-The Netherlands: adverse outcome pathways.
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Food for Thought ERC Edition, 17/03/2017, Brussels-Belgium: experience of an ERC Starting Grantee at VUB.
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Royal Academy for Overseas Sciences, 28/03/2017, Brussels-Belgium: hoe start ik een academische onderzoeksgroep op in Brazilië: ervaring van een jonge Belgische onderzoeker.
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British Toxicology Society Meeting, 03-05/04/2017, Liverpool-UK: adverse outcome pathways as tools to assess chemically induced liver toxicity.
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Research seminar, 24/04/2017, Brussels-Belgium: current topics in toxicology: adverse outcome pathways
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Symposium “AOPs: an alternative for risk assessment?” Société de Pharmaco-Toxicologie Cellulaire, 21/06/2017, Paris-France : development and validation of an AOP from bile salt pump inhibition to cholestasis.
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CAAT-Academy training “Updates on the hepatotoxicity AOP landscape and on the ADMET field”, 22-23/06/2017, Rennes-France, development and validation of an AOP from bile salt pump inhibition to cholestasis.
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Symposium “AOP course light”, UKEMS/BEMS/DEMS meeting, 25-28/06/2017, Leuven-Belgium: AOP background and principles.
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14th European ISSX meeting, 26-29/06/2017, Cologne-Germany: adverse outcome pathways as tools to assess drug-induced toxicity.
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10th World Congress Alternatives and Animal Use in the Life Sciences, 20-24/08/2017, Seattle-USA: omics-based in vitro verification of an adverse outcome pathway of cholestatic liver injury.
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10th World Congress Alternatives and Animal Use in the Life Sciences, 20-24/08/2017, Seattle-USA: the European Society of Toxicology In Vitro (ESTIV)’s activities in promoting in vitro and in silico computational toxicology.
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Science Xpression Workshop, 25-29/09/2017, Santiago de Compostella-Spain: preparing and giving a scientific presentation: tips and tricks.
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Science Xpression Workshop, 25-29/09/2017, Santiago de Compostella-Spain: writing a scientific abstract: tips and tricks.
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Science Xpression Workshop, 25-29/09/2017, Santiago de Compostella-Spain: preparing and presenting a scientific poster: tips and tricks.
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Gap Junction Conference: Therapeutic Applications, 28/09/2017, La Coruna-Spain: role of connexin hemichannels in acute and chronic liver disease.
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State-of-the-art lectures in Biomedicine, 04/10/2017, Antwerp-Belgium: adverse outcome pathways: novel tools in (eco)toxicology and risk assessment.
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Study day “Alternatives to animal experiments”, 05/10/2017, Brussels-Belgium: mechanistic toxicology as the basis for animal-free risk assessment.
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Congress “Non-animal methods for toxicokinetics”, 16-20/10/2017, Leiden-The Netherlands: AOP framework: where do kinetics come in?
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Seminar at the Environmental Protection Agency, 30/10/2017, Raleigh Durham-USA: development of a quantitative adverse outcome pathway network of cholestatic liver injury for animal-free chemical risk assessment.
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11th International Congress of Pharmaceutical Sciences, 15-18/11/2017, Ribeirão Preto-Brazil: liver-based in vitro models for pharmaco-toxicological testing.
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11th International Congress of Pharmaceutical Sciences, 15-18/11/2017, Ribeirão Preto-Brazil: the European Society of Toxicology In Vitro: overview and activities.
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Seminar “Animal testing for human therapeutics?”, 12/01/2018, Utrecht-The Netherlands: liver-based in vitro models for pharmaco-toxicological testing.
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Society of Toxicology meeting, 11-15/03/2018, San Antonio-USA: omics-based in vitro verification of an adverse outcome pathway of cholestatic liver injury.
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Applied in vitro toxicology course, 08-13/04/2018, Utrecht-The Netherlands: general in vitro cytotoxicity and cell death assays.
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Applied in vitro toxicology course, 08-13/04/2018, Utrecht-The Netherlands: liver-based models for in vitro toxicology purposes.
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Applied in vitro toxicology course, 08-13/04/2018, Utrecht-The Netherlands: emerging topics in in vitro toxicology: adverse outcome pathways.
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World Toxicologic Pathology Congress, 24-26/04/2018, São Paulo-Brazil: liver-based in vitro models for toxicity testing.
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PI Centric Event, 17/05/2018, Brussels-Belgium: CONNECT: connexin and pannexins channels as drug targets and biomarkers in acute and chronic liver disease.
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Galenus award ceremony, 29/05/2018, Brussels-Belgium: cellular communication as a novel pharmacological target for the treatment of liver disease.
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44th Annual Summer Meeting of the Toxicology Forum, 09-11/07/2018, Annapolis-USA: adverse outcome pathways as tools to predict liver toxicity in in vitro models.
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54th Congress of the European Societies of Toxicology, Brussels-Belgium, 02-05/09/2018: liver-based in vitro models for toxicity testing.
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54th Congress of the European Societies of Toxicology, Brussels-Belgium, 02-05/09/2018: pathway approaches in human toxicology: focus on liver toxicity AOPs.
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“From nanotoxicology to nanomedicine”, Tallinn-Estonia, 07/09/2018: liver-based in vitro models for toxicity testing.
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ASCCT-ESTIV Webinar Series, 20/09/2018, Brussels-Belgium: adverse outcome pathways: an update on progress and some near-term applications.
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Science Xpression Workshop, 24-28/09/2018, Santiago de Compostella-Spain: preparing and giving a scientific presentation: tips and tricks.
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Science Xpression Workshop, 24-28/09/2018, Santiago de Compostella-Spain: writing a scientific abstract: tips and tricks.
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Science Xpression Workshop, 24-28/09/2018, Santiago de Compostella-Spain: preparing and presenting a scientific poster: tips and tricks.
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Gap Junction Conference: Therapeutic Applications, 27/09/2018, La Coruna-Spain: role of connexin hemichannels in acute and chronic liver disease.
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State-of-the-art lectures in Biomedicine, 07/11/2018, Antwerp-Belgium: liver-based in vitro models for toxicity testing.
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“Fuckup night”, Brussels-Belgium, 29/11/2018: fuckup night.
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“Application of non-animal approaches for decision-making in chemical safety assessment” workshop, 10-11/12/2018, London-UK : the use of AOPs for in vitro prediction of liver toxicity.
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Postgraduate Education in Toxicology: Toxicogenomics, 21/02/2019, Maastricht-The Netherlands: adverse outcome pathways.
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Society of Toxicology meeting, 10-14/03/2019, Baltimore-USA: mitochondrial toxicity: a frequent key event in adverse outcome pathways.
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“Introduction to toxicology and ecotoxicology as the scientific basis for management of chemical risk” BelTox seminar, 19/03/2019, Brussels-Belgium: in vitro methods for hazard identification.
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VUB Pop-up seminar, 05/04/2019, Brussels-Belgium: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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Applied in vitro toxicology course, 14-19/04/2019, Bucharest-Romania: general in vitro cytotoxicity and cell death assays.
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Applied in vitro toxicology course, 14-19/04/2019, Bucharest-Romania: liver-based models for in vitro toxicology purposes.
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Applied in vitro toxicology course, 14-19/04/2019, Bucharest-Romania: emerging topics in in vitro toxicology: adverse outcome pathways.
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Research seminar, 02/05/2019, Split-Croatia: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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Molecular Toxicology Course, 26-29/06-2019, Izmir-Turkey: adverse outcome pathways: focus on mitotoxicity.
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Molecular Toxicology Course, 26-29/06-2019, Izmir-Turkey: liver-based in vitro models: tools for molecular toxicology research.
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International Gap Junction Conference, 27-31/07/2019, Victoria- Canada: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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55th Congress of the European Societies of Toxicology, 08-11/09/2019, Helsinki-Finland: adverse outcome pathways and beyond.
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8th Annual Meeting of the ASCCT "Computational toxicology: peeking into the clouds while keeping our feet on solid ground", 24-26/09/2019, Gaithersburg-USA: 2019-2020 conferences: ESTIV2020, WC11 and P2P.
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epaa workshop "New ideas for systemic toxicity", 01-02/10/2019, Brussels-Belgium: development and testing of a repeated dose toxicity ontology model for chemical risk assessment purposes: liver effects as a case study.
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EBTC-EFSA workshop "Advancing the application of evidence-based methods to construct mechanistic frameworks for the development and use of non-animal toxicity tests", 02-03/10/2019, Parma-Italy: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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Science Xpression Workshop, 07-11/10/2019, La Coruna-Spain: preparing and giving a scientific presentation: tips and tricks.
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Science Xpression Workshop, 07-11/10/2019, La Coruna-Spain: writing a scientific abstract: tips and tricks.
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Gap Junction Conference: connexin and pannexin channels in inflammation, tissue regeneration and cancer, 08/10/2019, La Coruna-Spain: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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10th International Congress of the Turkish Society of Toxicology, 16/10-19/10/2019, Antalya-Turkey: adverse outcome pathways associated with mitochondria.
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International Industrial and Environmental Toxicology Congress, 26/10-29/10/2019, Antalya-Turkey: liver-based in vitro models for toxicity testing.
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Pioneer-2-Policymaker Conference "Accelerating the transition towards animal-free innovations", 27-29/11/2019, Utrecht-The Netherlands: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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State-of-the-art lectures in Biomedicine, 18/12/2019, Antwerp-Belgium: liver-based in vitro models for toxicity testing.
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Seminar University of Wageningen, 16/01/2020, Wageningen-The Netherlands: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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Liver Systems Medicine Retreat, 29/01-31/01/2020, Hofgeismar-Germany: liver-based in vitro models for toxicity testing.
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Liver Systems Medicine Retreat, 29/01-31/01/2020, Hofgeismar-Germany: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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BelTox seminar “Introduction to toxicology and ecotoxicology as the scientific basis for management of chemical risk”, 18/02/2020, Brussels-Belgium: in vitro methods for hazard identification.
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OECD webinar, 09/07/2020: 3Rs projects funded by the European Commission: AOP case study.
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OpenTox2020 Virtual Conference, 21/09-25/09-2020: development, quantification and application of an adverse outcome pathway network of cholestatic liver injury.
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Applied in vitro toxicology course, 25-30/10/2020, Brussels-Belgium: general in vitro cytotoxicity and cell death assays.
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Applied in vitro toxicology course, 25-30/10/2020, Brussels-Belgium: liver-based models for in vitro toxicology purposes.
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Applied in vitro toxicology course, 25-30/10/2020, Brussels-Belgium: emerging topics in in vitro toxicology: adverse outcome pathways.
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Society for Risk Analysis Virtual Meeting, 13-17/12/2020: development, quantification and application of an adverse outcome pathway network of cholestatic liver injury.
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CIAO Covid-19 AOP Design Virtual Workshop, 27-28/01/2021: involvement of the liver in COVID-19.
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Janssen Pharmaceutica, 10/02/2021, webinar: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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Université Catholique de Louvain, 22/02/2021, webinar: liver-based in vitro models for toxicity testing and drug development.
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Universiteit Maastricht-The Netherlands, Postgraduate Education in Toxicology: Toxicogenomics, 04/03/2021, webinar: adverse outcome pathways.
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US FDA webmeeting, 05/03/2021: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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State-of-the-art lectures in Biomedicine, 17/03/2021, webinar: liver-based in vitro models for toxicity testing.
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Universiteit Groningen-The Netherlands, 14/04/2021, webinar: the use of adverse outcome pathways for in vitro prediction of liver toxicity induced by drugs.
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CIAO Covid-19 AOP Design Virtual Workshop, 28-29/04/2021: involvement of the liver in COVID-19.
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ONTOX webinar "AOP", 04/06/2021.
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Virtual Human Platform for Safety Assessment (VHP4Safety) online kick-off meeting, 18/06/2021: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Korea Institute of Toxicology, online presentation, 03/09/2021: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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Hearing Flemish Parliament, 22/09/2021: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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57th Congress of the European Societies of Toxicology (Virtual Conference), 27/09-01/10/2021: development and application of an adverse outcome pathway of cholestatic liver injury.
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ILSI Europe Annual Symposium, 05/10/2021: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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ASPIS cluster kick-off meeting, 04/11/2021, Brussels-Belgium: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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ERC Life Sciences event VUB, 10/11/2021, Brussels-Belgium: testimony of an ERC Grant holder in life sciences.
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3rd workshop on alternatives methods to the use of animals for toxicological studies of plant protection products for registration purposes, online presentation, 10-11/11/2021: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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The 34th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments, online presentation, 11-13/11/2021: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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BfR Symposium Challenges in Public Health Protection in the 21st Century: New Methods, Omics and Novel Concepts in Toxicology, online presentation, 15-17/11/2021: use of omics in AOP validation and application: liver toxicity as a case study.
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State-of-the-art lectures in Biomedicine, 17/11/2021, webinar: liver-based in vitro models for toxicity testing.
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2nd International Conference Series on 3Rs Research and Progress: Advances in Animal Models and Cutting-Edge Research in Alternatives, online presentation, 18-19/11/2021: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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Hogeschool Utrecht Online Symposium, 21/01/2022: role of Hogeschool Utrecht in international research initiatives: the European ONTOX project as a case study.
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ITF meeting European Medicines Agency, 24/01/2022: PANACHE: production of next generation peptidomimetics targeted towards pannexins and connexins as novel therapeutics in the treatment of inflammatory cardiovascular, hepatic and joint diseases.
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OECD webmeeting, 26/01/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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EFSA webmeeting, 14/02/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Eurogroup for Animals webmeeting, 21/02/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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PETA webmeeting, 24/02/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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HESI webmeeting, 28/02/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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ERPA webmeeting, 09/03/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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7th German Pharm-Tox Summit, online presentation, 07-10/03/2022: development, application and validation of AOPs: cholestatic liver injury as a case study.
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EFPIA webmeeting, 17/03/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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EMA webmeeting, 21/03/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Nestlé webmeeting, 24/03/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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HOBOTA kick-off meeting, 01/04/2022, Janssen Pharmaceutica, Beerse-Belgium: VUB team and expertise relevant to HOBOTA.
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In2TOX webinar, 19/04/2022: liver-based in vitro modelling.
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Universiteit Groningen-The Netherlands, 21/04/2022, webinar: the use of adverse outcome pathways for in vitro prediction of liver toxicity induced by drugs.
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Applied in vitro toxicology course, 06-11/06/2022, Belvaux-Luxembourg: general in vitro cytotoxicity and cell death assays.
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Applied in vitro toxicology course, 06-11/06/2022, Belvaux-Luxembourg: liver-based models for in vitro toxicology purposes.
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Applied in vitro toxicology course, 06-11/06/2022, Belvaux-Luxembourg: emerging topics in in vitro toxicology: adverse outcome pathways.
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NIEHS webmeeting, 23/06/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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OECD webmeeting, 24/06/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Charles River Laboratories webmeeting, 27/06/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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BE PARERE network webmeeting, 13/07/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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EchA webmeeting, 14/09/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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23rd EUSAAT Congress, 26-28/09/2022, Linz-Austria: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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3rd In Silico Toxicology Online Conference, 29/09/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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VHP4Safety-ONTOX workshop, 17/10/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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11th Congress of the Turkish Society of Toxicology, 02/11-05/11/2022, Antalya-Turkey: adverse outcome pathways for in vitro prediction of liver toxicity.
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The Danish 3R symposium, 08/11-09/11/2022, Copenhagen-Denmark: the European ONTOX project: safer chemicals using less chemicals.
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Latin American online Congress of Alternative Methods, 16/11-18/11/2022: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Mérieux NutriSciences webmeeting, 24/01/2023: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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ANSES webmeeting, 25/01/2023: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Seminar at Paul Scherrer Institute-Eidgenössische Technische Hochschule, 01/02/2023, Zurich-Switzerland: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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Seminar at Anadolu University, 09/02/2023, Eskişehir-Türkiye: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
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21st Century Toxicology: Sneak Preview of Ongoing Relevant Activities, 23/03/2023, Nashville-US: ONTOX project and ASPIS working group overview.
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Universiteit Groningen-The Netherlands, 20/04/2023, webinar: adverse outcome pathways for the in vitro prediction of drug-induced liver injury.
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HOBOTA meeting, 28/04/2023, Janssen Pharmaceutica, Beerse-Belgium: adverse outcome pathways for the in vitro prediction of drug-induced liver injury.
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IUTOX webinar, 24/05/2023: adverse outcome pathways as the basis for in vitro prediction of chemical-induced liver toxicity.
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ASCCT-ESTIV webinar, 24/05/2023: in vitro prediction of liver toxicity using adverse outcome pathways.
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Applied in vitro toxicology course, 29/05-02/06/2023, Bratislava-Slovakia: general in vitro cytotoxicity and cell death assays.
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Applied in vitro toxicology course, 29/05-02/06/2023, Bratislava-Slovakia: liver-based models for in vitro toxicology purposes.
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Applied in vitro toxicology course, 29/05-02/06/2023, Bratislava-Slovakia: emerging topics in in vitro toxicology: adverse outcome pathways.
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HESI-NC3Rs meeting: NAMs for safety assessment: from aspiration to implementation, 07/06-08/06/2023, London-United Kingdom: development and implementation of NAMs: the European ONTOX project.
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Seminar at SCK CEN, 22/06/2023, Mol-Belgium: effects of spaceflight conditions on the liver: focus on non-alcoholic fatty liver disease.
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Seminar at SCK CEN, 22/06/2023, Mol-Belgium: liver-based in vitro models for preclinical testing.
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2nd Microphysiological Systems World Summit, 26/06-30/06/2023, Berlin-Germany: ontologies as tools to support MPS-driven predictive toxicity screening: liver toxicity as a case study.
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International Colloquium on Gap Junctions and Cancer, 10/07-14/07/2023, São Paulo-Brazil: connexins, pannexins and their channels in liver cancer.
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Corteva Agriscience webmeeting, 21/08/2023: ONTOX: Ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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57th Congress of the European Societies of Toxicology, 10-13/09/2023, Ljubljana-Slovenia: ontologies as the basis for setting up animal-free test batteries: liver toxicity as a case study.
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EBTC/EFSA workshop, 26/09/2023, Parma-Italy: the European ONTOX project: goals and first results.
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EPA webmeeting, 12/10/2023: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Phillip Morris International webmeeting, 12/10/2023: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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EPA webmeeting, 16/11/2023: in vitro prediction of liver toxicity using adverse outcome pathways.
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University of Seoul, webmeeting, 22/11/2023: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Shell, webmeeting, 17/01/2024: ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Symposium "Adverse outcome pathways coming to life: exploring new ways to support risk assessments", 29/01/2024, Maastricht-The Netherlands: use of AOPs and ontologies in the ONTOX project.
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SaferWorldbyDesign: NextGen Basel 1: Next Generation Product Design and Risk Assessment, 01/03/2024, Basel-Switzerland: ontologies as the basis for setting up animal-free test batteries: liver toxicity as a case study.
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Seminar at ProtoQSAR, 12/04/2024, Valencia-Spain: ontologies as the basis for setting up animal-free test batteries: liver toxicity as a case study.
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Webinar Universiteit Groningen, 19/04/2024: adverse outcome pathways for in vitro prediction of drug-induced liver toxicity.
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EUROTOX webinar, 30/04/2024: (drug-induced) liver toxicity: types and mechanisms.
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Seminar at the Division of Liver Diseases of the Icahn School of Medicine at Mount Sinai, 10/05/2024, New York-USA: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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Molecular Toxicology Course, 22-24/05/2024, Izmir-Turkey: adverse outcome pathways: focus on mitotoxicity.
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Molecular Toxicology Course, 22-24/05/2024, Izmir-Turkey: liver-based in vitro models: tools for molecular toxicology research.
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ILSI Europe training "Advancements in toxicological hazard and risk assessment for food safety: exploring new approach methodologies and predictive models", 30/05/2024, Brussels-Belgium: general in vitro cytotoxicity and cell death assays.
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ILSI Europe training "Advancements in toxicological hazard and risk assessment for food safety: exploring new approach methodologies and predictive models", 30/05/2024, Brussels-Belgium: adverse outcome pathways for molecular toxicology research.
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22nd International Congress of the European Society of Toxicology In Vitro, 03-06/06/2024, Prague-Czech Republic: how to write a successful European project proposal: from idea to submission.
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22nd International Congress of the European Society of Toxicology In Vitro, 03-06/06/2024, Prague-Czech Republic: ontologies as the basis for setting up animal-free test batteries: liver toxicity as a case study.
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ASPIS Academy webinar, 21/06/2024: how to write a successful European project proposal: from idea to submission.
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58th Conference of the European Societies of Toxicology, 08-11/09/2024, Copenhagen-Denmark: finding European research funding and writing a competitive research proposal.
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58th Conference of the European Societies of Toxicology, 08-11/09/2024, Copenhagen-Denmark: ONTOX: overview and hazard identification strategy.
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ASPIS open symposium, 11-12/09/2024, Copenhagen-Denmark: the European ONTOX project: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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ASPIS open symposium, 11-12/09/2024, Copenhagen-Denmark: ONTOX coordinatorship August 2024-April 2026.
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5th Latin American Congress of Alternative Methods to the Use of Experimental Animals, 16-20/09/2024, Bogota-Colombia: cytotoxicity: mechanisms and in vitro assays.
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5th Latin American Congress of Alternative Methods to the Use of Experimental Animals, 16-20/09/2024, Bogota-Colombia: the European ONTOX project: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Online training course “3Rs in toxicity testing” within the educational program of the German Society of Toxicology, 23-27/09/2024: adverse outcome pathways.
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University of Seoul seminar, 15/10/2024, Seoul-South Korea: cytotoxicity: mechanisms and in vitro assays.
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University of Seoul seminar, 17/10/2024, Seoul-South Korea: the European ONTOX project: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Shell seminar, 30/10/2024, The Hague-The Netherlands: the European ONTOX project: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment.
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Applied in vitro toxicology course, 24/11-29/11/2024, Belvaux-Luxembourg: liver-based models for in vitro toxicology purposes.
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ISMIB Seminar Series University of Liverpool, 05/12/2024, Liverpool-United Kingdom: mechanistic toxicology as the basis for the development of new in vitro approaches for the safety testing of chemicals and drugs: liver toxicity as a case study.
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64th Society of Toxicology Meeting, 16-20/03/2025, Orlando-USA: effects of altered microgravity and cosmic radiation on the liver.
Poster presentations
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Cell signaling, transcription and translation as therapeutic targets, 30/01-02/02/2002, Luxemburg-Luxemburg: phase I biotransformation of Trichostatin A, a histone deacetylase inhibitor, in suspensions of freshly isolated rat hepatocytes, and in human and rat liver microsomes.
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Annual BelTox meeting, 29/11/2002, Brussels-Belgium: phase I biotransformation of Trichostatin A, a histone deacetylase inhibitor, in suspensions of freshly isolated rat hepatocytes, and in human and rat liver microsomes.
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Hepatocyte Users Group meeting, 12-13/11/2004, Valencia-Spain: the effect of Trichostatin A on gap junctional intercellular communication in primary cultures of rat hepatocytes.
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Discovery on Target: histone deacetylase inhibitors, 16-17/10/2007, Boston-USA: Trichostatin A enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes.
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1st annual carcinoGENOMICS consortium meeting, 06-08/11/2007, Valencia-Spain: Trichostatin A enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes.
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3rd annual meeting of the European Partnership for Alternative Approaches to Animal Testing, 03/11/2008, Brussels-Belgium: establishment of an in vitro model of liver cell death.
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ESNATS summer school, 22-27/09/2009, Zermatt-Switzerland: connexin32 hemichannels facilitate the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death.
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4th annual meeting of the European Partnership for Alternative Approaches to Animal Testing, 06/11/2009, Brussels-Belgium: data sharing on compound selection: a way to improve the outcome of research projects in the field of 3R-alternatives to animal testing.
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Cold Spring Harbor Asia Conference on Epigenetics, Chromatin and Transcription, 17-21/05/2010, Suzhou-China: the novel histone deacetylase inhibitor 4-Me2N-BAVAH enhances functional differentiation in cultures of primary hepatocytes.
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16th Conference of the European Society for Toxicology In Vitro, 02-04/09/2010, Linz-Austria: connexin32 hemichannels facilitate the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death.
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50th Society of Toxicology Meeting, 06-10/03/2011, Washington DC-USA: connexin32 hemichannels facilitate the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death.
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International Gap Junction Conference, 06-11/08/2011, Ghent-Belgium: connexin43 signalling contributes to spontaneous apoptosis in cultures of primary hepatocytes.
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8th World Congress on Alternatives and Animal Use in the Life Sciences, 21-25/08/2011, Montréal-Canada: connexin43 signalling contributes to spontaneous apoptosis in cultures of primary hepatocytes.
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Annual meeting of the Safety Evaluation Ultimately Replacing Animal Testing project cluster, 08-09/02/2012, Lisbon-Portugal: connexin43 signalling contributes to spontaneous apoptosis in cultures of primary hepatocytes.
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Summer School of the Safety Evaluation Ultimately Replacing Animal Testing project cluster, 04-08/06/2012, Lisbon-Portugal: connexin43 signalling contributes to spontaneous apoptosis in cultures of primary hepatocytes.
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International Gap Junction Conference, 13-18/07/2013, Charleston-USA: connexin43 signalling triggers dedifferentiation in cultures of primary hepatocytes by facilitating spontaneous apoptosis.
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Annual meeting of the Safety Evaluation Ultimately Replacing Animal Testing project cluster, 05-06/02/2014, Barcelona-Spain: development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.
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Society of Toxicology meeting, 23-27/03/2014, Phoenix-USA: development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.
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NC3R workshop, 08-09/05/2014, London-UK: development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.
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SEURAT summer school, 08-10/06/2014, Egmond aan Zee-The Netherlands: development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.
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18th Conference of the European Society for Toxicology In Vitro, 10-13/06/2014, Egmond aan Zee-The Netherlands: development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.
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25th Asian Pacific Association for the Study of the Liver, 20-24/02/2016, Tokyo-Japan: inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity in mouse.
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NC3R workshop, 28/04/2016, London-UK: in vitro verification of an adverse outcome pathway of cholestasis.
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67th American Association for the Study of Liver Diseases Meeting, 11-15/11/2016, Boston-USA: in vitro verification of an adverse outcome pathway of cholestasis.
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67th American Association for the Study of Liver Diseases Meeting, 11-15/11/2016, Boston-USA: pannexin1 channel inhibition attenuates neutrophil recruitment upon acetaminophen-induced hepatotoxicity.
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53rd Congress of the European Societies of Toxicology, 10-13/09/2017, Bratislava-Slovakia: omics-based in vitro verification of an adverse outcome pathway of cholestatic liver injury.
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CEFIC LRI workshop, 14-15/11/2018, Brussels-Belgium: development and testing of a repeated dose toxicity ontology model for chemical risk assessment purposes: liver effects as a case study.
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15th IUTOX International Congress of Toxicology, 15-18/07/2019, Honolulu-USA: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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55th Congress of the European Societies of Toxicology, 08-11/09/2019, Helsinki-Finland: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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The Liver Meeting, 08-12/11/2019, Boston-USA: connexin hemichannels and pannexin channels as drug targets in liver toxicity and disease.
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14th IEEE International Conference on Semantic Computing, 03-05/02/2020, San Diego-USA: facilitating data curation: a solution developed in the toxicology domain.
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9th ASCCT meeting, 20-23/10/2020, virtual meeting: a robust mechanistically-based in silico profiler for cholestatic liver injury.
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Society of Toxicology meeting, 12-26/03/2021, virtual meeting: representations of liver toxicity knowledge by chemotypes based on ontology approach to support biological and chemical grouping in chemical safety assessment.
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ESPEN virtual congress, 09-14/09/2021: type and frequency of hepatotoxic medication and use of parenteral nutrition in a tertiary care intensive unit.
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14th Australian Peptide Conference, 08/05-13/05/2022, Gold Coast-Australia: design and synthesis of stapled 10Panx1 analogs for use in inflammation and cardiovascular diseases.
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Joint Meeting of the French and Belgian Peptides and Proteins Societies, 29/05-03/06/2022, Port-Leucate-Frankrijk: design and synthesis of stapled 10Panx1 analogs for use in inflammation and cardiovascular diseases.
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Joint Meeting of the French and Belgian Peptides and Proteins Societies, 29/05-03/06/2022, Port-Leucate-Frankrijk: structure-activity relationship study of the pannexin1 channel inhibitor 10Panx1.
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Joint Meeting of the French and Belgian Peptides and Proteins Societies, 29/05-03/06/2022, Port-Leucate-Frankrijk: peptidomimetic inhibitors of connexin43 hemichannels.
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Summer School of Bioinformatics, Cambridge, United Kingdom, 13/06-17/06/2022: from human physiology to toxicity prediction: working on the ONTOX project.
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UCLouvain master thesis defense event, 23/06/2022, Brussels-Belgium: set up and maintenance of a cholangiocyte 3D spheroid model.
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17th Belgian Organic Synthesis Symposium, 03/07-08/07/2022, Namur-Belgium: peptidomimetic inhibitors of connexin43 hemichannels.
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ESPEN Congress, 03-06/09/2022, Vienna-Austria: sepsis and hepatotoxic drugs contribute to liver test disturbances in critically ill patients receiving parenteral nutrition, cumulative volume of parenteral nutrition does not.
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ESPEN Congress, 03-06/09/2022, Vienna-Austria: carbohydrates induce liver test disturbances during treatment of critically ill patients, lipids and proteins don’t.
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Virtual Physiological Human Conference, 06-09/09/2022, Porto-Portugal: developing a physiological map as a framework to study chemical-induced liver steatosis.
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36th European and 12th International Peptide Symposium, 28/08-02/09/2022, Sitges-Spain: structure-activity relationship study of the pannexin1 channel inhibitor 10Panx1.
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36th European and 12th International Peptide Symposium, 28/08-02/09/2022, Sitges-Spain: peptidomimetic inhibitors of connexin43 hemichannels.
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LS2 Swiss Physiology meeting, 06/09/2022, Bern-Switzerland: stapled 10Panx1 analogs as a new class of anti-inflammatory Panx1 channel inhibitors.
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IUTOX XVI International Congress of Toxicology, 18-21/09/2022, Maastricht-The Netherlands: benchmark dose response modelling of gene co-expression networks in hepatocytes exposed to known inducers of liver steatosis, cholestasis and necrosis.
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IUTOX XVI International Congress of Toxicology, 18-21/09/2022, Maastricht-The Netherlands: physiology-based framework to study chemical-induced cholestasis.
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IUTOX XVI International Congress of Toxicology, 18-21/09/2022, Maastricht-The Netherlands: physiological maps: a benchmark tool for adverse outcome pathways and a cornerstone for the development of disease ontologies.
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IUTOX XVI International Congress of Toxicology, 18-21/09/2022, Maastricht-The Netherlands: artificial intelligence and open science to build adverse outcome pathways and perform toxicological risk assessment.
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5th Swiss Vascular Research Symposium, 03/11/2022, Zurich-Switzerland: Stapled 10Panx1 analogs as a new class of anti-inflammatory Panx1 channel inhibitors.
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21st Conference of the European Society for Toxicology In Vitro, 21-25/11/2022, Sitges-Spain: exploring the use of spheroid cultures of human liver cells for the mechanistic testing of carcinogenic compounds.
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21st Conference of the European Society for Toxicology In Vitro, 21-25/11/2022, Sitges-Spain: connexin-based channel activity is not specifically altered by hepatocarcinogenic chemicals.
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21st Conference of the European Society for Toxicology In Vitro, 21-25/11/2022, Sitges-Spain: an adverse outcome pathway network for liver steatosis induced by chemicals.
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21st Conference of the European Society for Toxicology In Vitro, 21-25/11/2022, Sitges-Spain: update and optimization of an adverse outcome pathway network of chemical-induced cholestasis.
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21st Conference of the European Society for Toxicology In Vitro, 21-25/11/2022, Sitges-Spain: applying machine-learning approaches to identify key genes associated with drug-induced cholestasis.
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21st Conference of the European Society for Toxicology In Vitro, 21-25/11/2022, Sitges-Spain: designing physiological maps as a tool to study liver toxicology.
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Summer School on Medicinal Chemistry and Chemical Biology in Drug Discovery: the Pharma Perspective, 19-21/06/2023, Santiago de Compostela-Spain: the European project PANACHE: synergizing in silico, in vitro and in vivo methods to develop innovative inhibitors of membrane-bound proteins as potential anti-inflammatory drugs.
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International Society for Heart Research Congress,10-13/07/2023, Porto-Portugal: a new class of Panx1 channel inhibitors exters anti-inflammatory effects on the endothelium.
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12th World Congress on Alternatives and Animal Use in the Life Sciences, 27-31/08/2023, Niagara Falls-Canada: an adverse outcome pathway network for liver steatosis induced by chemicals.
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12th World Congress on Alternatives and Animal Use in the Life Sciences, 27-31/08/2023, Niagara Falls-Canada: update and optimization of an adverse outcome pathway network of chemical-induced cholestasis.
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12th World Congress on Alternatives and Animal Use in the Life Sciences, 27-31/08/2023, Niagara Falls-Canada: applying machine-learning approaches to identify key genes associated with drug-induced cholestasis.
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57th Conference of the European Societies of Toxicology, 10-13/09/2023, Ljubljana-Slovenia: high-content imaging of human hepatic spheroids for studying compounds with cholestatic liability.
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57th Conference of the European Societies of Toxicology, 10-13/09/2023, Ljubljana-Slovenia: an updated adverse outcome pathway network on chemical-induced liver steatosis.
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57th Conference of the European Societies of Toxicology, 10-13/09/2023, Ljubljana-Slovenia: accessible online methods and tools for assessing chemical exposure in humans: a systematic scoping review for the ONTOX project.
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57th Conference of the European Societies of Toxicology, 10-13/09/2023, Ljubljana-Slovenia: novel clinical phenotypes and chemical classifications in drug-induced cholestasis.
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57th Conference of the European Societies of Toxicology, 10-13/09/2023, Ljubljana-Slovenia: probabilistic read-across assessment of 2-MCPD.
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45th ESPEN Congress on Clinical Nutrition and Metabolism, 11-14/09/2023, Lyon-France: determination and differentiating the impact of parenteral nutrition, sepsis, acute heart failure and hepatotoxic drugs on liver tests in ICU patients: a retrospective study.
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23rd meeting of the French Group on Peptides and Proteins, 17-21/09/2023, Fournols-France: cyclic lipidated peptide inhibitors for cardiac endothelium targeting based on the C-terminal tail of connexin43.
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Joint 3R symposium, 19-21/09/2023, Brussels-Belgium: development of human liver cancer 3D spheroid cultures for assessment of nanoplastic toxicity.
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Symposium “Cholestatic liver disorders: from bed to benchside”, 21-22/09/2023, Leuven-Belgium: bile secretion physiological map and the cholestasis ontology as innovative tools for understanding the mechanisms of cholestatic liver disorders.
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Symposium “Cholestatic liver disorders: from bed to benchside”, 21-22/09/2023, Leuven-Belgium: effects of bile duct ligation on cell junctions in mouse liver.
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Symposium “Cholestatic liver disorders: from bed to benchside”, 21-22/09/2023, Leuven-Belgium: characterization of biological responses of human hepatic spheroids to compounds with cholestasis liability using high-throughput transcriptomics.
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Symposium “Cholestatic liver disorders: from bed to benchside”, 21-22/09/2023, Leuven-Belgium: human liver spheroid co-cultures as a tool to study parenteral nutrition-associated liver toxicity.
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Symposium “Cholestatic liver disorders: from bed to benchside”, 21-22/09/2023, Leuven-Belgium: set-up of an in vitro 3D spheroid co-culture model to predict cholestatic drug-induced liver injury.
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Symposium “Cholestatic liver disorders: from bed to benchside”, 21-22/09/2023, Leuven-Belgium: role of bile acid transporters and connexins in drug-induced cholestasis.
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Symposium “Cholestatic liver disorders: from bed to benchside”, 21-22/09/2023, Leuven-Belgium: elucidation of molecular initiating events in PFAS-mediated cholestatic liver injury.
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5th Meeting of Translational Hepatology, 05-06/10/2023, Sevilla-Spanje: novel clinical phenotypes in cholestatic DILI, associated drugs, and new prognosis predictive models: analysis of a database of 432 patients developed by collaborative literature review and machine learning support.
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Swiss Society for Microvascular Research Congress, 13/11/2023, Lausanne-Switzerland: a new Panx1 channel inhibitor decreases monocyte adhesion to the endothelium.
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Society of Toxicology Meeting, 10-14/03/2024, Salt Lake City-USA: ASPIS: animal-free safety assessment of chemicals: project cluster for implementation of novel strategies.
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epaa NAM Designathon workshop, 20-22/03/2024, Ispra-Italy: development of a test battery for the detection of induction of molecular initiating events of cholestatic liver toxicity induced by chemical compounds.
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epaa NAM Designathon workshop, 20-22/03/2024, Ispra-Italy: NAM to identify low, medium and high concern of carboxylic acid-induced hepatic steatosis.
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Disease Maps Community Meeting, 25-27/03/2024, Belvaux-Luxembourg: semi-automated workflow to accelerate AOP network construction using SBGN elements: a pilot study.
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Disease Maps Community Meeting, 25-27/03/2024, Belvaux-Luxembourg: FAIR-compliant physiological mapping as a basis for building disease ontology maps: case studies in toxicology.
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Helsinki Chemical Forum, 10/04/2024, Helsinki-Finland: ASPIS - Animal-free Safety Assessment of Chemicals: Project Cluster for Implementation of Novel Strategies.
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3rd Annual ONTOX meeting, 24-25/04/2024, Utrecht-The Netherlands: set-up of a human-based in vitro test battery for the identification of cholestasis inducing chemicals.
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3rd Annual ONTOX meeting, 24-25/04/2024, Utrecht-The Netherlands: development of a test battery for the detection of induction of molecular initiating events of cholestatic liver toxicity induced by chemical compounds.
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3rd Annual ONTOX meeting, 24-25/04/2024, Utrecht-The Netherlands: the ability of a stem cell-based in vitro model to detect liver steatotic potential of diverse chemicals.
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3rd Annual ONTOX meeting, 24-25/04/2024, Utrecht-The Netherlands: from physiological maps to disease ontology maps using a systems biology approach.
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3rd Microphysiological Systems World Summit, 10-14/06/2024, Seattle-USA: evaluation of functional candidate biomarkers of non-genotoxic hepatocarcinogenicity in human liver spheroid co-cultures.
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International Gap Junction Conference, 27-31/07/2024, Arlington-USA: nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury.
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37th European Peptide Symposium and 14th International Peptide Symposium, 25-29/08/2024, Florence-Italy: cyclic peptides as connexin43 and pannexin1 inhibitors.
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LS2 Swiss Physiology meeting, 03/09/2024, Fribourg-Switzerland: a new stable Panx1 peptidomimetic for the prevention of myocardial ischemia/reperfusion injury.
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VHP Conference, 04/09-06/09/2024, Stuttgart-Germany: Building disease ontology maps: in silico tools for applications in toxicology.
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58th Conference of the European Societies of Toxicology, 08-11/09/2024, Copenhagen-Denmark: distribution kinetics of triazole fungicides in an in vitro liver steatosis model.
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58th Conference of the European Societies of Toxicology, 08-11/09/2024, Copenhagen-Denmark: optimization of predictive liver toxicity modeling based on the drug-induced cholestasis index.
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58th Conference of the European Societies of Toxicology, 08-11/09/2024, Copenhagen-Denmark: elucidation of molecular initiating events in PFAS-mediated cholestatic liver injury.
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58th Conference of the European Societies of Toxicology, 08-11/09/2024, Copenhagen-Denmark: using a systems biology approach to construct adverse outcome pathway networks aligned with the FAIR principles.
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58th Conference of the European Societies of Toxicology, 08-11/09/2024, Copenhagen-Denmark: development of a hepatic spheroid co-culture model for prediction of cholestatic drug-induced liver injury.
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ASPIS Open Symposium, 11-12/09/2024, Copenhagen-Denmark: distribution kinetics of triazole fungicides in an in vitro liver steatosis model.