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TEAM

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CURRENT MEMBERS

Professors

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Full professor (100%)

Mathieu Vinken

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Assistant professor (10%) / postdoctoral researcher (90%)

Andrés Tabernilla

Postdoctoral researchers

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Development of a new liver-based in vitro system to detect idiosyncratic liver injury

To be completed in 2028

Promoter: Mathieu Vinken

Jiang Jian

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Development of a new liver-based in vitro system to detect cholestatic chemicals

To be completed in 2026

Promoter: Mathieu Vinken

Julen Sanz Serrano

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In vitro testing of new inhibitors of Cx43 hemichannels and Panx1 channels

To be completed in 2025

Promoter: Mathieu Vinken

Andrés Tabernilla

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In vivo testing of new inhibitors of Cx43 hemichannels and Panx1 channels

To be completed in 2025

Promoter: Mathieu Vinken

Prashant Kadam

Doctoral researchers

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Risk assessment of chemical mixtures: liver toxicity as a case study

To be defended in 2026

Promoters: Mathieu Vinken, Nynke Kramer, Jochem Louisse

 Ellen Callewaert

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Development of a mechanism-based and artificial intelligence-fed in vitro test platform to predict chemical-induced cholestatic liver injury

To be defended in 2027

Promoters: Mathieu Vinken, Julen Sanz Serrano

Annika Drees

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Optimization of Panx1 nanobodies towards clinical treatment of inflammatory liver disease

To be defended in 2027

Promoters: Mathieu Vinken, Raf Van Campenhout

Daan Peeters

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Effects of microplastics on liver in vitro and in vivo

To be defended in 2025

Promoters: Mathieu Vinken, Lindsey Devisscher

Sybren De Boever

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Effects of food supplements on liver in vitro and in vivo

To be defended in 2025

Promoters: Mathieu Vinken, Lindsey Devisscher

Amy Maerten

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Development of new inhibitors of Cx43 hemichannels and Panx1 channels as novel therapeutics for the treatment of liver disease

To be defended in 2022

Promoters: Mathieu Vinken, Nick Devoogdt, Serge Muyldermans

Co-promotor: Timo De Groof

Raf Van Campenhout

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In vitro detection of steatotic chemicals

To be defended in 2025

Promoters: Mathieu Vinken, Tamara Vanhaecke

Co-promotor: Joery De Kock

Anouk Verhoeven

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In vitro testing of the hepatotoxic/hepatoprotective potential of herbal medicines and dietary supplements

To be defended in 2026

Promoters: Mathieu Vinken, Hilmi Orhan

Co-promotors: Kristiaan Demeyer, Andrés Tabernilla

Batuhan Yildiz

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Role of cellular communication mediated by pannexin1 channels in non-alcoholic fatty liver disease induced by microgravity and radiation

To be defended in 2027

Promoter: Mathieu Vinken

Co-promotors: Bjorn Baselet, Kevin Tabury

Ben Cools

 

 

Technicians

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Fien Haenen

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Arne Loosen

 

 

Project manager

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Julia Dominika Zajac

 
 
 
 
 
 
 
 
 
 
 
       
 
 

 
 
FORMER TEAM MEMBERS

Dr. Alanah Pieters

Dr. Elif Ince Ergüç

Dr. Vânia Vilas-Boas

Dr. Bruna dos Santos Rodrigues

M. Sci. Emma Arnesdotter

M. Sci. Sara Crespo-Yanguas

M. Sci. Kaat Leroy

Pharm. Anne Caufriez

Pharm. Axelle Cooreman

Pharm. Eva Gijbels

Pharm. Michaël Maes

Pharm. Joost Willebrords

Miss Ana Rita Coelho Gomes

Miss Dinja De Win

Miss Tâmara Prandini

Miss Tineke Vanhalewyn

Miss Manon Wery

FINISHED POSTDOCTORAL PROJECTS

Role of connexin and pannexin (hemi)channels in liver cancer

Tereza Cristina da Silva: completed 31/03/2017

Promoters: Mathieu Vinken, Bruno Cogliati

Role of connexin and pannexin (hemi)channels in hepatitis

Isabel Veloso Alves Pereira: completed 31/03/2017

Promoters: Mathieu Vinken, Bruno Cogliati

Development of a primary hepatocyte spheroid culture system for the detection of chemical-induced cholestatic liver injury

Vânia Vilas-Boas: completed 31/12/2020

Promoter: Mathieu Vinken

Role of connexin and pannexin (hemi)channels in cholestasis

Alanah Pieters: completed 31/01/2022

Promoter: Mathieu Vinken

Identification of natural inhibitors of pannexin channels

Elif Ince Ergüç: completed 31/01/2023

Promoter: Mathieu Vinken

Characterization of new mechanisms of cholestasis as the basis for animal-free prediction of drug-induced liver injury

Bruna dos Santos Rodrigues: completed 30/09/2023

Promoter: Mathieu Vinken

In vitro investigation of the hepatotoxic potential of total parenteral nutrition

Milos Mihajlovic: completed 31/12/2024

Promoter: Mathieu Vinken

 

 

FINISHED DOCTORAL PROJECTS

Evaluation of carcinogen-modified global gene expression profiles in liver-based in vitro models with focus on primary hepatocyte cultures

Tatyana Doktorova: defended 16/03/2012

Promoters: Mathieu Vinken, Tamara Vanhaecke, Vera Rogiers

 

Development of a differentiated hepatic in vitro system for long-term pharmaco-toxicological studies based on (epi)genetic modification of primary hepatocytes

Eva Ramboer: defended 15/10/2015

Promoters: Mathieu Vinken, Tamara Vanhaecke, Vera Rogiers

 

The role of connexins, pannexins and their channels in acute liver failure

Michaël Maes: defended 17/10/2017

Promoters: Mathieu Vinken, Bruno Cogliati

 

The role of connexins, pannexins and their channels in non-alcoholic steatohepatitis

Joost Willebrords: defended 29/01/2018

Promoters: Mathieu Vinken, Bruno Cogliati

 

The role of connexins, pannexins and their channels in liver fibrosis

Sara Crespo Yanguas: defended 25/10/2018

Promoters: Mathieu Vinken, Bruno Cogliati

 

Connexin43 hemichannels as druggable targets for future anti-seizure medication

Laura Walrave: defended 24/01/2019

Promoter: Ilse Smolders

Co-promoters: Mathieu Vinken, Luc Leybaert

Modelling and prediction of chemical-induced human cholestatic liver injury: a mechanistic approach

Eva Gijbels: defended 01/12/2021

Promoters: Mathieu Vinken, Lindsey Devisscher

Co-promoter: Tamara Vanhaecke

Towards next generation risk assessment of chemicals: liver toxicity as a case study

Emma Arnesdotter: defended 19/05/2022

Promoters: Mathieu Vinken, Tamara Vanhaecke

Role of connexins, pannexins and their channels in liver cancer

Kaat Leroy: defended 31/01/2023

Promoters: Mathieu Vinken, Bruno Cogliati

Identification, development and in vitro testing of pannexin1 channel inhibitors 

Anne Caufriez: defended 03/10/2023

Promoters: Mathieu Vinken, Steven Ballet

Role of connexins and their channels in cholestasis

Axelle Cooreman: defended 11/10/2023

Promoters: Mathieu Vinken, Pieter Annaert

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